
Cauldron Ferm, an advanced biomanufacturer, announced that the company has received $13.25 million in a Series A2 funding round and has been included on Fast Company’s 2026 list of the World’s Most Innovative Companies. The round was led by Main Sequence Ventures, with participation from Horizons Ventures, SOSV and NGS Super, bringing Cauldron’s total funding to $26 million.
The new capital and Fast Company recognition underscore growing momentum behind Cauldron’s continuous “hyper-fermentation” platform, a proprietary technology designed to deliver step-change improvements in bioprocess efficiency.
Biomanufacturing uses living cells as programmable factories, in which bioengineered microbes convert simple inputs such as sugars into valuable products.
“For biomanufacturing to compete in industrial sectors, bioproducts have to deliver on costs, scale, and quality. Bioprocess innovation is how we get there,” says Michele Stansfield, co-founder and CEO of Cauldron. “We’re honored to be backed by a dedicated group of experienced investors and proud to be recognized as one of [Fast Company‘s] World’s Most Innovative Companies. This milestone reflects the impact of our platform at a time when governments and corporations are urgently seeking competitive bio-based solutions to address supply chain pressure.”
The new capital will enable Cauldron to meet growing demand from governments and corporations investing in biomanufacturing infrastructure. To accelerate scale up of Cauldron’s technology for commercial production, the company is working with corporate partners to evaluate retrofitting existing facilities to deploy hyper-fermentation at partner sites. Cauldron has also secured non-dilutive government grants in Australia and the U.S. to support expansion of Cauldron’s demo-scale operations in Orange, NSW and planning for industrial-scale production.
Founded in 2022, Cauldron has rapidly progressed from early validation to commercial proof points. In 2025, the World Economic Forum named Cauldron a “Technology Pioneer” for its potential to reshape manufacturing.